2-(4-bromo-3-(trifluoromethyl)phenyl)propan-2-amine hydrochloride - Names and Identifiers
2-(4-bromo-3-(trifluoromethyl)phenyl)propan-2-amine hydrochloride - Physico-chemical Properties
2-(4-bromo-3-(trifluoromethyl)phenyl)propan-2-amine hydrochloride - Introduction
2-(4-bromo-3-(trifluoromethyl) phenol) propan-2-amine (2-(4-bromo-3-(trifluoromethyl) phenol) propan-2-amine) is an organic compound with the following properties:
Nature:
-Molecular formula: C11H14BrClF3N
-Molecular weight: 345.59g/mol
-Appearance: White crystalline solid
-Melting point: 108-112 ° C
-Solubility: Soluble in ethanol and water
Use:
- 2-(4-bromo-3-(trifluoromethyl)phenyl)propan-2-amine is widely used in pharmaceutical and chemical research.
-It is often used as an intermediate for certain drugs or for the synthesis of important organic compounds.
Method:
-There are many specific synthesis methods. Here is a common synthesis method:
1. First, 4-bromoacetophenone was reacted with a hydrogen chloride dehydrating agent to obtain 4-bromoacetophenone chloride.
2. 4-bromoacetophenone chloride is then reacted with trifluoromethylaniline to produce 2-(4-bromo-3-(trifluoromethyl) phenyl) propyl ketone.
3. Finally, 2-(4-bromo-3-(trifluoromethyl)phenyl) propyl ketone is reacted with ammonia gas and hydrochloric acid to produce 2-(4-bromo-3-(trifluoromethyl)phenyl)propan-2-amine hydrochloride.
Safety Information:
-Proper laboratory procedures need to be followed when using or handling the compound.
-It is an organic compound with certain toxicity and should be handled with care.
-Avoid contact with skin, eyes and respiratory tract.
-Use personal protective equipment such as gloves, goggles and protective masks.
-Store the compound in a dry, well-ventilated place away from fire and high temperatures.
Last Update：2024-04-09 21:01:54